CALECIM Professional Serum | PTT-6® Regenerative Stem Cell Serum 6 x 5ml

CALECIM® Professional Serum is one of the most advanced regenerative serums in professional skincare — and a quiet powerhouse for skin that's ageing, fragile, or recovering from a treatment. At its heart is PTT-6®, a proprietary complex of more than 3,000 naturally occurring proteins — growth factors, cytokines, exosomes, fibronectins, soluble collagen and hyaluronic acid — derived from cord-lining stem cells. Think of them as "youth messages": signals that encourage your skin's own cells to renew, rebuild and behave as they did when they were younger.

This is the most concentrated PTT-6® formula in the CALECIM range. A few drops, pressed into clean skin, support a firmer, smoother, more even and luminous-looking complexion over time, and help soften the appearance of fine lines. Because it works with your skin's natural repair processes rather than forcing exfoliation, many people find it a gentle, well-tolerated alternative to more irritating actives.

It's also the serum aesthetic clinics reach for after treatments. Applied after microneedling, laser, radiofrequency or peels, its anti-inflammatory proteins help calm the look of redness and support the skin's recovery — practitioners report noticeably less downtime and visibly more comfortable skin.

What's inside — PTT-6®

• Growth factors & cytokines — the messaging signals that prompt skin cells to renew and rebuild
• Exosomes — tiny vesicles that carry cell-to-cell communication for repair
• Soluble collagen & hyaluronic acid — support hydration, plumpness and a smoother surface
• Fibronectins & glycoproteins — the binding "scaffolding" that helps skin structure and strength
• Albumin — helps maintain moisture balance for a plump, youthful-looking complexion

The evidence
In peer-reviewed laboratory testing on human skin cells (Journal of Drugs in Dermatology, 2023), PTT-6®'s cord-lining proteins increased skin-cell production of hyaluronic acid by 83% and elastin by 56%. In a randomised, double-blind clinical trial after CO₂ laser resurfacing, the CALECIM regimen was safe and well tolerated, with significantly less burning and stinging and a trend toward less redness and improved wrinkling. After procedures, practitioners report calmer skin within 15–30 minutes and downtime reduced by around half. CALECIM's science is supported by 12 papers across 3 peer-reviewed journals.

Who it's for
All skin types, including mature, thin or fragile skin, and anyone recovering from an in-clinic or at-home skin treatment.

Three ways to use

1. Daily — apply one pipette to clean skin, morning and/or night, before your other serums and creams.
2. After at-home treatments — press a few pipettes into the skin after microneedling, a peel or exfoliation.
3. After clinical treatments — a clinic favourite following microneedling, laser, RF or peels.

Layer water-based products first, then this serum, then heavier creams; finish with SPF each morning. It works well alongside vitamin C, retinol, AHAs and BHAs.

Ethically and sustainably sourced
CALECIM®'s PTT-6® comes from red deer umbilical cord-lining stem cells — chosen as the richest, highest-purity source. The active contains only the proteins these cells secrete, with no DNA.

Good to know

• Why it's pink. The natural pink hue is a built-in pH indicator that monitors the freshness of the active proteins. The shade can vary from light orange to deep pink — all normal. If it turns yellow, clear or cloudy, stop using it and contact us. Keep it cool, below 33°C.
• Fragrance-free. Any faint natural scent comes from the high concentration of active ingredient and fades within minutes.
• Pregnancy & breastfeeding. Considered suitable, but we recommend checking with your doctor first.
• Active acne. Best avoided on actively breaking-out skin — speak to your dermatologist first.